As the owner of a therapeutically-oriented yoga studio, I encounter people every day who are using yoga and meditation as an alternative and holistic treatment to help them ease stress, alleviate symptoms, decrease pain, calm their nervous system, and just feel better! As a vegan of 8 years and a holistic health coach, I am passionate about using plants/food as medicine after experiencing and observing immense health benefits within myself and others when we look to the earth for natural healing.
After participating in a conversation recently with three of my regular therapeutic yoga students who all suffer the pain of fibromyalgia, arthritis and other autoimmune conditions, it seemed only natural to merge my interests. I have decided to step up to the plate and expand the offerings at my yoga center in order to provide even greater, complimentary assistance to those who are struggling in the face of the aforementioned heath challenges, that are seemingly all too common these days.
Inspired by my intense passion for assisting others with their holistic health and wellness, I am excited to partner with Hempworx in order to offer the members of the Blossoming Soul/Seeds of Compassion community the "World’s Purest CBD Oil." We will now be bringing this natural healing remedy to our community, both in-studio and via direct-ship (straight to your door) online ordering, so I wanted to share some of the amazing benefits and details with you....
THE NEW OIL RUSH
After a 50 year hiatus, the "miracle plant that is sweeping the nation" is back and flying off the shelves. Now legal in all 50 states after the passing of the "Farm Bill" in 2014, Forbes recently predicted that the CBD industry will explode by 700% before 2020. Why? Because reports of its efficacy are nothing short of AMAZING!
Used in medicine for millennia, cannabis and chemically related compounds have come back to being considered of immense therapeutic value. A prominent compound found in cannabis, CBD, or cannabidiol, has shown to treat numerous diseases. Researchers believe that in view of the very low toxicity and the generally benign side effects of CBD, neglecting or denying CBD benefits and its clinical potential is simply unacceptable.
WHAT IS CBD?
CBD is one of over 60 compounds found in cannabis that belong to a class of ingredients called cannabinoids. Until recently, THC (tetrahydrocannabinol) was getting most of the attention because it’s the ingredient in cannabis that produces mind-altering effects in users, but CBD is also present in high concentrations — and the medical world is realizing that its list of medical benefits continues to grow.
CBD is the major nonpsychoactive component of Cannabis sativa. According to a 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits include acting in some experimental models as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent, and is therefore a potential medicine for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and depression.
HOW DOES CBD WORK?
As you may know, inside the human body there’s the endocannabinoid system, with receptors spread throughout the brain and body. Research is beginning to show that CBD is different than other well-studied cannabinoids in terms of how it interacts with this system. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior.
CB1 receptors are widely distributed throughout the endocannibinoid system, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. CB2 receptors are found mostly in the immune system, and they seem to reduce inflammation and certain kinds of pain. Although cannabinoids all have similar structures, they display a wide array of actions at each of the different receptors.
However, scientists are finding out that CBD has very little effect on CB1 and CB2 receptors, which probably explains why it doesn’t have mind-altering effects, unlike THC, which positively regulates the CB1 receptor. That’s why most marijuana grown for recreational purposes are typically very low in CBD and high in THC. CBD does not directly stimulate these receptors.
Instead, it activates other receptors, like the vanilloid, adenosine and serotonin receptors. By activating the TRPV-1 receptor for example, cannabidiol plays a role in the mediation of body temperature, pain perception and inflammation. Then, CBD inhibits the FAAH enzyme, a compound that activates the CB1 receptor. By doing so, CBD minimizes the activation of CB1 by THC, reducing its psychoactive effects.
The activation of adenosine receptors by CBD gives the anti-anxiety and anti-inflammatory effects of cannabidiol. Adenosine receptors are also involved in the release of dopamine and glutamate, two neurotransmitters that play major roles inside the body. Dopamine is involved in cognition, motor control, motivation and reward mechanisms, while glutamate is one of the major mediators of excitatory signals, being involved in memory, learning and cognition.
High concentrations of CBD have been shown to activate the 5-HT1A serotonin receptor, exerting anti-depressant effects. The same receptor is involved in a series of processes from pain perception, appetite, nausea and anxiety to sleep and addiction mechanisms.
Finally, CBD blocks CPR55 signaling, decreasing bone re-absorption and cancer cell proliferation. GPR55 is widely present inside the brain, being linked with the modulation of bone density and blood pressure, as well as with cancer cell proliferation.
As previously said, CBD blocks the psychoactive action of THC, this being one of the reasons it’s generally considered advantageous to combine CBD and THC when for treatment purposes. However, the positive effects of cannabidiol are not dependent on the presence of THC, so you can still take advantage of the health benefits of CBD by purchasing products that contain only non-psychoactive CBD.
STUDIES SHOW 8 PROVEN HEALTH BENEFITS OF CBD
1. Relieves Pain and Inflammation
Among common CBD benefits, natural pain relief tops the list for many. Evidence suggests that cannabinoids may prove useful in pain modulation by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found that CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other nonpsychoactive components of marijuana may represent a novel class of therapeutic agents for the treatment of chronic pain.
According to a 2007 meta-analysis conducted in Canada, the combination of CBD and THC buccal spray was found to be effective in treating neuropathic pain in multiple sclerosis, which can be debilitating for 50 to 70 percent of MS patients.
2. Has Antipsychotic Effects
Research shows that CBD benefits include producing antipsychotic effects. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal studies. Additionally, studies show that CBD prevents human experimental psychosis and is effective in open case reports and clinical trials in patients with schizophrenia, with a remarkable safety profile.
3. Reduces Anxiety
Studies using animal models of anxiety and involving healthy volunteers clearly suggest an anxiolytic-like effect of CBD. Cannabidiol has shown to reduce anxiety in patients with social anxiety disorder and researchers suggest that it may also be effective for panic disorder, obsessive compulsive disorder, social anxiety disorder and post-traumatic stress disorder.
A 2011 study aimed to compare the effects of a simulation public speaking test on healthy control patients and treatment-native patients with social anxiety disorder. A total of 24 never-treated patients with social anxiety disorder were given either CBD or placebo 1.5 hours before the test. Researchers found that pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alertness in anticipation of their speech. The placebo group presented higher anxiety, cognitive impairment and discomfort.
4. Helps to Fight Cancer
Several scientific reports demonstrate that CBD benefits include possessing antiproliferative, pro-apoptotic effects that inhibit cancer cell migration, adhesion and invasion. A 2006 study published in the Journal of Pharmacology and Experimental Therapeutics found for the first time that CBD potently and selectively inhibited the growth of different breast tumor cell lines and exhibited significantly less potency in non-cancer cells.
In 2011, researchers added light on the cellular mechanism through which CBD induces cell death in breast cancer cells. They showed that CBD induced a concentration-dependent cell death of both oestrogen receptor-positive and oestrogen receptor-negative breast cancer cells. They also found that the effective concentrations of CBD in tumor cells have little effect on non-tumorigenic, mammary cells.
CBD behaves as a non-toxic compound and studies show that doses of 700 milligrams per day for 6 weeks did not show any overt toxicity in humans, suggesting that it can be used for prolonged treatment. Not only does the research show that CBD benefits including being effective in fighting breast cancer cells, data also suggests that it can be used to inhibit the invasion of lung and colon cancer, plus it possesses anti-tumor properties in gliomas and has been used to treat leukemia.
5. Relieves Nausea
Cannabis has been used for centuries for the suppression of nausea and vomiting. Research has revealed that among more than 80 cannabinoid compounds found in marijuana, both the intoxicant THC and the non-intoxicant CBD helps to get rid of nausea and vomiting in animal studies. A 2012 study published in the British Journal of Pharmacology found that CBD benefits including possessing anti-nausea and antiemetic effects when it was administered to rats. Researchers found that CBD acts in a diphasic manner, meaning that in low doses it suppresses toxin-induced vomiting, but in high doses it increases nausea or has no effect.
6. May Treat Seizures and Other Neurological Disorders
A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of cannabidiol-enriched cannabis to treat their child’s seizures. Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of CBD-enriched cannabis. The average number of anti-epileptic drugs tried before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking CBD cannabis. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction. Other beneficial effects included increased alertness, better mood and improved sleep; while side effects included drowsiness and fatigue.
Later in 2014, researchers reported on preliminary results of a study involving children with treatment-resistant epilepsies in an expanded access “compassionate use program.” Patients received a purified 98 percent oil-based CBD extract called Epidiolex, which is made by GW Pharmaceuticals. After 3 months of treatment, 39 percent of the 23 patients had more than a 50 percent reduction in seizures, with a 32 percent median reduction. These preliminary results support the animal studies and survey reports that CBD may be a promising treatment for treatment-resistant epilepsy and it is generally well-tolerated in doses up to 25 milligrams per kilogram of body weight.
7. Lowers Incidence of Diabetes
A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice. CBD benefits also showed a significant reduction of plasma levels of pro-inflammatory cytokines. A histological examination of the pancreatic islets of the CBD-treated mice revealed significantly reduced insulitis.
In 2013, the American Journal of Medicine published a study that highlighted the impact of marijuana use on glucose, insulin and insulin resistance among U.S. adults. The study included 4,657 adult men and women from the National Health and Nutritional Examination Survey from 2005 to 2010. Of the participants, 579 were current marijuana users and 1,975 were past users. The researchers found that current marijuana use was associated with 16 percent lower fasting insulin levels. They also found significant associations between marijuana use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms.
8. Promotes Cardiovascular Health
A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability (which causes leaky gut) associated with such environments.
HOW TO GET STARTED
If you would like to discover how HempWorx's Non-GMO, Organic, FDA-Complaint, and legal in all 50 states, CBD Oil might help you, you can learn more or place a direct ship order by visiting: www.hempworx.com/taralavoie
If you are a fellow Health Coach, Yoga Therapist, Holistic Health Practitioner, or Natural Health Enthusiast interested in offering CBD Oil to your clients as an affiliate or a wholesaler, you can sign up for a free tour at www.hempworxbizop.com/TaraLavoie
Happy & Healthy Hemping!
Pertwee RG., Pharmacology of cannabinoid receptor ligands, Current medical chemistry, 1999, 6(8):635-64; http://www.ncbi.nlm.nih.gov/pubmed/10469884
Ashton JC, Wright JL, McPartland JM, Tyndall JD, Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB-2 selective antagonists, Current medical chemistry, 2008, 15(14):1428-43; http://www.ncbi.nlm.nih.gov/pubmed/18537620
Racz I, Nadal X, Alferink J et al., Crucial role of CB2 cannabinoid receptor in the regulation of central immune responses during neuropathic pain, The Journal of Neuroscience, 2008, 28(46):12125-35; http://www.jneurosci.org/content/28/46/12125.long
Costa B., Giagnoni G. et al., Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation, British Journal of Pharmacology, 2004, 143(2):247-50; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575333/
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. HempWorx LLC & Blossoming Soul Yoga & Integrative Wellness LLC assume no responsibility for the improper use of and self-diagnosis and/or treatment using these products. Our products should not be confused with prescription medicine and they should not be used as a substitute for medically supervised therapy. If you suspect you suffer from clinical deficiencies, consult a licensed, qualified medical doctor. You must be at least 18 years old to visit our website and make product purchases. We do not make any health claims about our products at HempWorx LLC/Blossoming Soul Yoga & Integrative Wellness LLC. Before taking our products, it’s wise to check with your physician or medical doctor. It is especially important for people who are: pregnant, chronically ill, elderly, under 18, taking prescription or over the counter medicines. None of the information on our website is intended to be an enticement to purchase and may not be construed as medical advice or instruction. The use of any of our products for any reason, other than to increase general health & wellness, is neither, implied nor advocated by HempWorx LLC or Blossoming Soul Yoga & Integrative Wellness LLC.